Phentermine-topiramate is contraindicated in which condition?

Phentermine-topiramate is a combination medication commonly prescribed for weight management. It functions as an appetite suppressor and is utilized in patients who are obese or overweight with comorbid conditions. However, there are specific contraindications to its use, one of which is glaucoma.

The reason for this contraindication is that topiramate, one of the components of Phentermine-topiramate, can induce an increase in intraocular pressure, potentially worsening glaucoma or precipitating acute angle-closure glaucoma. Patients with a history of glaucoma must be carefully evaluated before considering treatment with this combination medication due to the risk of deteriorating their ocular condition.

In contrast, hypertension and diabetes are not outright contraindications for this medication, although caution should be exercised in managing these conditions concurrently. Obesity is the primary indication for prescribing Phentermine-topiramate, as the medication is specifically designed to aid in weight loss efforts.