American Board of Internal Medicine (ABIM) Certification Practice Exam

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Which tests are essential to monitor after administering calcitriol to manage secondary hyperparathyroidism?

  1. Blood glucose and hemoglobin

  2. Serum electrolytes

  3. Calcium and phosphorus

  4. Renal function tests

The correct answer is: Calcium and phosphorus

Monitoring calcium and phosphorus levels is crucial after administering calcitriol, especially in the context of managing secondary hyperparathyroidism. Calcitriol, being the active form of vitamin D, increases intestinal absorption of calcium and phosphorus. Therefore, it is essential to measure these levels to avoid complications such as hypercalcemia or hyperphosphatemia. Excessive calcium levels can lead to various clinical issues, including cardiovascular problems, while high phosphorus levels can contribute to vascular calcification, particularly in patients with chronic kidney disease. Regularly checking these parameters allows for timely adjustments to therapy and helps in mitigating any potential adverse effects associated with changes in calcium and phosphorus levels induced by calcitriol.